T cell activation assay - explanation of measures

3rd (Public) Challenge
1

Hi CMI-PB team,

Could you provide some resources / information where we could find out more about the AIM assay - specifically, what are PHA, PT, and TT ?

Thanks,

Nicky

3

Hi @Nicky_Thrupp,

Certainly! Here are some resources that might be helpful:

  1. General Information on the AIM Assay: PLOS ONE paper
  2. T Cell Response Overview: Review
  3. T-cell Response in B. pertussis Vaccination and Infection:
  1. T-cell Responses Specific to CMI-PB Data: CMI-PB T-cell response manuscript

I have also tagged Lisa (@Lisa_Willemsen), who may have additional insights or resources.

Best,
Pramod